Efficient Virus Assembly, but Not Infectivity, Determines the Magnitude of Hepatitis C Virus-Induced Interferon Alpha Responses of Plasmacytoid Dendritic Cells

Worldwide, approximately 160 million people are chronically infected with hepatitis C virus (HCV), seven distinct genotypes of which are discriminated. The hallmarks of HCV are its genetic variability and the divergent courses of hepatitis C progression in patients. We assessed whether intragenotypi...

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Bibliographic Details
Published in:J Virol
Main Authors: Grabski, Elena, Wappler, Ilka, Pfaender, Stephanie, Steinmann, Eike, Haid, Sibylle, Dzionek, Andrzej, Pietschmann, Thomas, Kalinke, Ulrich
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337522/
https://ncbi.nlm.nih.gov/pubmed/25552725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03229-14
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