5-Bromo-2′-deoxyuridine Potentiation of Transformation of Rat-Embryo Cells Induced In Vitro by 3-Methylcholanthrene: Induction of Rat Leukemia Virus gs Antigen in Transformed Cells

Low-passage rat-embryo cells were not transformed by 3-methylcholanthrene or by 5-bromo-2′ deoxyuridine. However, prior treatment with bromodeoxyuridine, followed by treatment with methylcholanthrene, resulted in cell transformation about three subpassages after removal of the carcinogen. RNA-direct...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Freeman, Aaron E., Gilden, Raymond V., Vernon, Mina Lee, Wolford, Ronald G., Hugunin, Patricia E., Huebner, Robert J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1973
Témata:	Biological Sciences: Immunology
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4134493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.8.2415
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