Transcriptional Alterations of ET-1 Axis and DNA Damage in Lung Tissue of a Rat Obesity Model

Obesity has been implicated in the development of many cancers. This can lead to genome damage, especially in the form of double-strand break, the presence of which is now easily detected through nuclear phosphorylation of histone H2AX (γ-H2AX) focus assay. Recently, the endothelin (ET) axis has als...

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Detalhes bibliográficos
Publicado no:DNA Cell Biol
Main Authors: Del Ry, Silvia, Cabiati, Manuela, Salvadori, Costanza, Guiducci, Letizia, Caselli, Chiara, Prescimone, Tommaso, Facioni, Maria Sole, Azzarà, Alessia, Chiaramonte, Anna, Mazzoni, Stefano, Bruschi, Fabrizio, Giannessi, Daniela, Scarpato, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Research ArticlesMolecular Genetics/Genomics/Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337466/
https://ncbi.nlm.nih.gov/pubmed/25517973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2014.2705
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