Antidrug antibodies against TNF-blocking agents: correlations between disease activity, hypersensitivity reactions, and different classes of immunoglobulins

Although anti-TNF drugs have changed the clinical course of rheumatoid arthritis (RA), survival rates and resistance-to-therapy data confirm that about 30% of RA patients fail to respond. The aim of this study was to evaluate the correlations between the development of antidrug antibodies, specific...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biologics
Autori principali: Benucci, Maurizio, Li Gobbi, Francesca, Meacci, Francesca, Manfredi, Mariangela, Infantino, Maria, Severino, Maurizio, Testi, Sergio, Sarzi-Puttini, Piercarlo, Ricci, Cristian, Atzeni, Fabiola
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337417/
https://ncbi.nlm.nih.gov/pubmed/25733803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S69606
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