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Silencing MaxiK Activity in Corporal Smooth Muscle Cells Initiates Compensatory Mechanisms to Maintain Calcium Homeostasis

INTRODUCTION: The MaxiK potassium channel is regulated by voltage and intracellular calcium, and plays a critical role in regulating intracellular calcium concentration ([Ca(2+)](i)), which is the ultimate determinant of smooth muscle tone. Tight control of corpus cavernosum smooth muscle (CCSM) ton...

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Bibliographische Detailangaben
Veröffentlicht in:J Sex Med
Hauptverfasser: Calenda, Giulia, Suadicani, Sylvia Ottilie, Iglesias, Rodolfo, Spray, David Conover, Melman, Arnold, Davies, Kelvin Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337397/
https://ncbi.nlm.nih.gov/pubmed/21269393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1743-6109.2010.02180.x
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