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Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport

Repeated cycles of chronic intermittent ethanol (CIE) exposure increase voluntary consumption of ethanol in mice. Previous work has shown that extracellular glutamate in the nucleus accumbens (NAc) is significantly elevated in ethanol-dependent mice and that pharmacologically manipulating glutamate...

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Pubblicato in:Front Pharmacol
Autori principali: Griffin, William C., Ramachandra, Vorani S., Knackstedt, Lori A., Becker, Howard C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337330/
https://ncbi.nlm.nih.gov/pubmed/25755641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00027
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