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Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport

Repeated cycles of chronic intermittent ethanol (CIE) exposure increase voluntary consumption of ethanol in mice. Previous work has shown that extracellular glutamate in the nucleus accumbens (NAc) is significantly elevated in ethanol-dependent mice and that pharmacologically manipulating glutamate...

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Publicat a:Front Pharmacol
Autors principals: Griffin, William C., Ramachandra, Vorani S., Knackstedt, Lori A., Becker, Howard C.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337330/
https://ncbi.nlm.nih.gov/pubmed/25755641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00027
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