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Influence of Guanine Nucleotides and Elongation Factors on Interaction of Release Factors with the Ribosome

Release of formylmethionine from the reticulocyte ribosomal substrate, f[(3)H]Met-tRNA·ribosome, is promoted by reticulocyte release factor (RF). The initial rate of this reaction is stimulated by GTP but inhibited by GDPCP. Formation of an RF·UA[(3)H]A(2)·ribosome complex is a measure of the bindin...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Tate, W. P., Beaudet, A. L., Caskey, C. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1973
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433733/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4525170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.8.2350
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