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Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of multiple joints. The central pathogenesis of RA is the proliferation of synovial fibroblasts in response to inflammatory cytokines. However, some of the targeted therapies for inflammation reactions d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Yin, Geng, Wang, Ying, Cen, Xiao-min, Yang, Min, Liang, Yan, Xie, Qi-bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337269/
https://ncbi.nlm.nih.gov/pubmed/25741130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/460310
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