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The Initial Uridine of Primary piRNAs Does not Create the Tenth Adenine That is the Hallmark of Secondary piRNAs
PIWI-interacting RNAs (piRNAs) silence transposons in animal germ cells. PIWI proteins bind and amplify piRNAs via the “Ping-Pong” pathway. Because PIWI proteins cleave RNAs between target nucleotides t10 and t11—the nucleotides paired to piRNA guide positions g10 and g11—the first ten nucleotides o...
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| Publicado en: | Mol Cell |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337030/ https://ncbi.nlm.nih.gov/pubmed/25453759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.10.016 |
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