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Towards a mechanistic understanding of pathological anxiety: the dorsal medial prefrontal-amygdala ‘aversive amplification’ circuit in unmedicated generalized and social anxiety disorders

BACKGROUND: We have delineated, across four prior studies, the role of positive dorsal medial prefrontal/anterior cingulate cortex (dmPFC/ACC)-amygdala circuit coupling during aversive processing in healthy individuals under stress. This translational circuit, termed the ‘aversive amplification circ...

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Detalhes bibliográficos
Publicado no:Lancet Psychiatry
Main Authors: Robinson, Oliver J, Krimsky, Marissa, Lieberman, Lynne, Allen, Phillip, Vytal, Katherine, Grillon, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337019/
https://ncbi.nlm.nih.gov/pubmed/25722962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2215-0366(14)70305-0
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