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Structure of human cytoplasmic dynein-2 primed for its powerstroke

Members of the dynein family, consisting of cytoplasmic and axonemal isoforms, are motors that move towards the minus ends of microtubules. Cytoplasmic dynein-1 (dynein-1) plays roles in mitosis and cellular cargo transport(1), and is implicated in viral infections(2) and neurodegenerative diseases(...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Schmidt, Helgo, Zalyte, Ruta, Urnavicius, Linas, Carter, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336856/
https://ncbi.nlm.nih.gov/pubmed/25470043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14023
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