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Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion
BACKGROUND: Varying the rate of continuous intravenous infusions of 5-fluorouracil (5FU) chemotherapy over a 24-hour period has been reported to improve patient outcomes. It has been hypothesized that circadian variation in drug disposition is a contributing factor. We analyzed 5-FU concentrations d...
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Publicado no: | BMC Cancer |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336691/ https://ncbi.nlm.nih.gov/pubmed/25885822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1075-6 |
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