Small Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain

Chromobox homolog 7 (CBX7) plays an important role in gene transcription in a wide array of cellular processes, ranging from stem cell self-renewal and differentiation to tumor progression. CBX7 functions through its N-terminal chromodomain (ChD), which recognizes tri-methylated lysine 27 of histone...

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Publicado no:Chem Biol
Main Authors: Ren, Chunyan, Morohashi, Keita, Plotnikov, Alexander N., Jakoncic, Jean, Smith, Steven G., Li, Jiaojie, Zeng, Lei, Rodriguez, Yoel, Stojanoff, Vivian, Walsh, Martin, Zhou, Ming-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336573/
https://ncbi.nlm.nih.gov/pubmed/25660273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.11.021
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