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Comparable mRNA expression of inflammatory markers but lower claudin-1 mRNA levels in foreskin tissue of HSV-2 seropositive versus seronegative asymptomatic Kenyan young men

OBJECTIVES: Skin biopsies from local sites of herpes simplex virus 2 (HSV-2)-induced ulcers can show infiltrates of inflammatory cells several months after macroscopic healing. We hypothesise that foreskin tissue samples of asymptomatic HSV-2 seropositive men had remaining signs of inflammation at t...

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Pubblicato in:BMJ Open
Autori principali: Röhl, Maria, Tjernlund, Annelie, Mehta, Supriya D, Pettersson, Pernilla, Bailey, Robert C, Broliden, Kristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336463/
https://ncbi.nlm.nih.gov/pubmed/25694458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-006627
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