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Stereospecific Binding of the Potent Narcotic Analgesic [(3)H]Etorphine to Rat-Brain Homogenate

Etorphine, the most potent narcotic analgesic known, was labeled with tritium by catalytic exchange. This drug exhibits stereospecific, saturable binding to rat-brain homogenate. At saturation, the stereospecific binding is 0.1-0.15 pmol/mg of protein. Specific binding is inhibited high salt concent...

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Detalhes bibliográficos
Main Authors: Simon, Eric J., Hiller, Jacob M., Edelman, Irit
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433639/
https://ncbi.nlm.nih.gov/pubmed/4516196
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