Rational Development of an Attenuated Recombinant Cyprinid Herpesvirus 3 Vaccine Using Prokaryotic Mutagenesis and In Vivo Bioluminescent Imaging

Cyprinid herpesvirus 3 (CyHV-3) is causing severe economic losses worldwide in common and koi carp industries, and a safe and efficacious attenuated vaccine compatible with mass vaccination is needed. We produced single deleted recombinants using prokaryotic mutagenesis. When producing a recombinant...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Boutier, Maxime, Ronsmans, Maygane, Ouyang, Ping, Fournier, Guillaume, Reschner, Anca, Rakus, Krzysztof, Wilkie, Gavin S., Farnir, Frédéric, Bayrou, Calixte, Lieffrig, François, Li, Hong, Desmecht, Daniel, Davison, Andrew J., Vanderplasschen, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336323/
https://ncbi.nlm.nih.gov/pubmed/25700279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004690
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