Effect of a selective neutrophil elastase inhibitor on mortality and ventilator-free days in patients with increased extravascular lung water: a post hoc analysis of the PiCCO Pulmonary Edema Study

BACKGROUND: Neutrophil elastase plays an important role in the development and progression of acute respiratory distress syndrome (ARDS). Although the selective elastase inhibitor, sivelestat, is widely used in Japan for treating ARDS patients, its effectiveness remains controversial. The aim of the...

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Vydáno v:J Intensive Care
Hlavní autoři: Tagami, Takashi, Tosa, Ryoichi, Omura, Mariko, Fukushima, Hidetada, Kaneko, Tadashi, Endo, Tomoyuki, Rinka, Hiroshi, Murai, Akira, Yamaguchi, Junko, Yoshikawa, Kazuhide, Saito, Nobuyuki, Uzu, Hideaki, Kase, Yoichi, Takatori, Makoto, Izumino, Hiroo, Nakamura, Toshiaki, Seo, Ryutarou, Kitazawa, Yasuhide, Sugita, Manabu, Takahashi, Hiroyuki, Kuroki, Yuichi, Irahara, Takayuki, Kanemura, Takashi, Yokota, Hiroyuki, Kushimoto, Shigeki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336272/
https://ncbi.nlm.nih.gov/pubmed/25705423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40560-014-0067-y
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