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A phase I–II evaluation of veliparib (NSC#737664), topotecan, and filgrastim or pegfilgrastim in the treatment of persistent or recurrent carcinoma of the uterine cervix: An NRG Oncology/Gynecologic Oncology Group study

PURPOSE: To evaluate the tolerability and efficacy of poly(ADP-ribose) polymerase (PARP) inhibition by veliparib during cytotoxic topotecan administration with filgrastim or pegfilgrastim neutrophil support in women with persistent or recurrent uterine cervix cancer. EXPERIMENTAL DESIGN: This phase...

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Detalhes bibliográficos
Publicado no:Int J Gynecol Cancer
Main Authors: Kunos, Charles, Deng, Wei, Dawson, Dawn, Lea, Jayanthi S., Zanotti, Kristine M., Gray, Heidi J., Bender, David P., Guaglianone, Perry P., Carter, Jori S., Moore, Kathleen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336206/
https://ncbi.nlm.nih.gov/pubmed/25594147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IGC.0000000000000380
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