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Growing recognition of the role for rare missense substitutions in breast cancer susceptibility

Most cancer susceptibility genes function as tumor suppressors; accordingly, the focus of mutation screening in breast cancer families has been to identify protein-truncating mutations. However, it is now clear that, for some breast cancer susceptibility genes, a significant proportion of the burden...

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Detalhes bibliográficos
Publicado no:Biomark Med
Main Authors: Tavtigian, Sean V, Chenevix-Trench, Georgia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336165/
https://ncbi.nlm.nih.gov/pubmed/24796624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/bmm.13.143
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