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Growing recognition of the role for rare missense substitutions in breast cancer susceptibility
Most cancer susceptibility genes function as tumor suppressors; accordingly, the focus of mutation screening in breast cancer families has been to identify protein-truncating mutations. However, it is now clear that, for some breast cancer susceptibility genes, a significant proportion of the burden...
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| Veröffentlicht in: | Biomark Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336165/ https://ncbi.nlm.nih.gov/pubmed/24796624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/bmm.13.143 |
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