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Development and validation of risk index for cognitive decline using blood-derived markers

OBJECTIVE: We sought to develop and validate a risk index for prospective cognitive decline in older adults based on blood-derived markers. METHODS: The index was based on 8 markers that have been previously associated with cognitive aging: APOE genotype, plasma β-amyloid 42/40 ratio, telomere lengt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurology
Hauptverfasser: Nettiksimmons, Jasmine, Ayonayon, Hilsa, Harris, Tamara, Phillips, Caroline, Rosano, Caterina, Satterfield, Suzanne, Yaffe, Kristine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336104/
https://ncbi.nlm.nih.gov/pubmed/25609760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001263
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