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Evolution of a Second Gene for β-Galactosidase in Escherichia coli

Mutants of E. coli K12 with deletions of the β-galactosidase gene (lacZ) can reacquire the ability to hydrolyze β-galactosides during prolonged intense selection for growth on lactose. Full lactose competence is restored through a sequence of at least five mutations. Cell extracts of these derived s...

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Detalhes bibliográficos
Main Authors: Campbell, John H., Lengyel, Judith A., Langridge, John
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433609/
https://ncbi.nlm.nih.gov/pubmed/4124306
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