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Triheptanoin improves brain energy metabolism in patients with Huntington disease

OBJECTIVE: Based on our previous work in Huntington disease (HD) showing improved energy metabolism in muscle by providing substrates to the Krebs cycle, we wished to obtain a proof-of-concept of the therapeutic benefit of triheptanoin using a functional biomarker of brain energy metabolism validate...

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Publicat a:Neurology
Autors principals: Adanyeguh, Isaac Mawusi, Rinaldi, Daisy, Henry, Pierre-Gilles, Caillet, Samantha, Valabregue, Romain, Durr, Alexandra, Mochel, Fanny
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336068/
https://ncbi.nlm.nih.gov/pubmed/25568297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001214
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