Identification and Deconvolution of Cross-Resistance Signals from Antimalarial Compounds Using Multidrug-Resistant Plasmodium falciparum Strains

Plasmodium falciparum, the most deadly agent of malaria, displays a wide variety of resistance mechanisms in the field. The ability of antimalarial compounds in development to overcome these must therefore be carefully evaluated to ensure uncompromised activity against real-life parasites. We report...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Chugh, Monika, Scheurer, Christian, Sax, Sibylle, Bilsland, Elizabeth, van Schalkwyk, Donelly A., Wicht, Kathryn J., Hofmann, Natalie, Sharma, Anil, Bashyam, Sridevi, Singh, Shivendra, Oliver, Stephen G., Egan, Timothy J., Malhotra, Pawan, Sutherland, Colin J., Beck, Hans-Peter, Wittlin, Sergio, Spangenberg, Thomas, Ding, Xavier C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335906/
https://ncbi.nlm.nih.gov/pubmed/25487796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03265-14
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