Population Pharmacokinetics of Micafungin and Its Metabolites M1 and M5 in Children and Adolescents

The aim of this analysis was to identify therapeutic micafungin regimens for children that produce the same micafungin exposures known to be effective for the prevention and treatment of Candida infections in adults. Pediatric pharmacokinetic data from 229 patients between the ages of 4 months and &...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Hope, William W., Kaibara, Atsunori, Roy, Michael, Arrieta, Antonio, Azie, Nkechi, Kovanda, Laura L., Benjamin, Daniel K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335897/
https://ncbi.nlm.nih.gov/pubmed/25421470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03736-14
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