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Temporal and Seasonal Changes of Genetic Polymorphisms Associated with Altered Drug Susceptibility to Chloroquine, Lumefantrine, and Quinine in Guinea-Bissau between 2003 and 2012

In 2008, artemether-lumefantrine was introduced in Guinea-Bissau, West Africa, but quinine has also been commonly prescribed for the treatment of uncomplicated Plasmodium falciparum malaria. An efficacious high-dose chloroquine treatment regimen was used previously. Temporal and seasonal changes of...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jovel, Irina Tatiana, Kofoed, Poul-Erik, Rombo, Lars, Rodrigues, Amabelia, Ursing, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335894/
https://ncbi.nlm.nih.gov/pubmed/25421474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03554-14
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