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Antiviral Potential of ERK/MAPK and PI3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis

Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus, and infections with this virus can result in acute respiratory syndrome with renal failure. Globally, MERS-CoV has been responsible for 877 laboratory-confirmed infections, including 317 deaths, since September 2...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kindrachuk, Jason, Ork, Britini, Hart, Brit J., Mazur, Steven, Holbrook, Michael R., Frieman, Matthew B., Traynor, Dawn, Johnson, Reed F., Dyall, Julie, Kuhn, Jens H., Olinger, Gene G., Hensley, Lisa E., Jahrling, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335870/
https://ncbi.nlm.nih.gov/pubmed/25487801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03659-14
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