Tenofovir Monotherapy versus Tenofovir plus Lamivudine or Telbivudine Combination Therapy in Treatment of Lamivudine-Resistant Chronic Hepatitis B

Tenofovir disoproxil fumarate (TDF) monotherapy is a therapeutic option for chronic hepatitis B (CHB) patients infected with hepatitis B virus (HBV) variants resistant to lamivudine (LAM). We evaluated the antiviral efficacy and safety of TDF alone compared to those of TDF plus LAM or telbivudine (L...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Lee, Yun Bin, Jung, Eun Uk, Kim, Bo Hyun, Lee, Jeong-Hoon, Cho, Hyeki, Ahn, Hongkeun, Choi, Won-Mook, Cho, Young Youn, Lee, Minjong, Yoo, Jeong-Ju, Cho, Yuri, Lee, Dong Hyeon, Cho, Eun Ju, Yu, Su Jong, Park, Sung Jae, Kim, Yoon Jun, Park, Joong-Won, Lee, Youn Jae, Kim, Chang-Min, Yoon, Jung-Hwan, Kim, Chung Yong, Lee, Hyo-Suk
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335865/
https://ncbi.nlm.nih.gov/pubmed/25421484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04454-14
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