The Novel Immunotherapeutic Oligodeoxynucleotide IMT504 Protects Neutropenic Animals from Fatal Pseudomonas aeruginosa Bacteremia and Sepsis

IMT504 is a novel immunomodulatory oligonucleotide that has shown immunotherapeutic properties in early preclinical and clinical studies. IMT504 was tested in a neutropenic rat model of Pseudomonas aeruginosa bacteremia and sepsis. This animal system recapitulates many of the pathological processes...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chahin, Abdullah, Opal, Steven M., Zorzopulos, Jorge, Jobes, David V., Migdady, Yazan, Yamamoto, Michelle, Parejo, Nicholas, Palardy, John E., Horn, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335857/
https://ncbi.nlm.nih.gov/pubmed/25512413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03923-14
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