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Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand.

T-cell activation by an immunogenic peptide can be antagonized by nonstimulatory analogs of that peptide. We investigated this T-cell receptor antagonism by using staphylococcal enterotoxin superantigen to stimulate hemoglobin-specific helper T (Th) cells because its activation pathway may differ fr...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Evavold, B D, Sloan-Lancaster, J, Allen, P M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8134391/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.2300
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