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The role of the insulin-like growth factor-1 system in breast cancer
IGF-1 is a potent mitogen of major importance in the mammary gland. IGF-1 binding to the cognate receptor, IGF-1R, triggers a signaling cascade leading to proliferative and anti-apoptotic events. Although many of the relevant molecular pathways and intracellular cascades remain to be elucidated, a g...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335664/ https://ncbi.nlm.nih.gov/pubmed/25743390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0291-7 |
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