African Glucose-6-Phosphate Dehydrogenase Alleles Associated with Protection from Severe Malaria in Heterozygous Females in Tanzania

X-linked Glucose-6-phosphate dehydrogenase (G6PD) A- deficiency is prevalent in sub-Saharan Africa populations, and has been associated with protection from severe malaria. Whether females and/or males are protected by G6PD deficiency is uncertain, due in part to G6PD and malaria phenotypic complexi...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Manjurano, Alphaxard, Sepulveda, Nuno, Nadjm, Behzad, Mtove, George, Wangai, Hannah, Maxwell, Caroline, Olomi, Raimos, Reyburn, Hugh, Riley, Eleanor M., Drakeley, Christopher J., Clark, Taane G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335500/
https://ncbi.nlm.nih.gov/pubmed/25671784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004960
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