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Synthesis of Guanosine Tetra- and Pentaphosphate Requires the Presence of a Codon-Specific, Uncharged Transfer Ribonucleic Acid in the Acceptor Site of Ribosomes

The nucleotides ppGpp and pppGpp accumulate when wild-type, but not rel(-), strains of Escherichia coli are starved for required amino acids. These compounds are synthesized on ribosomes, in the presence of the product of the rel gene, from GDP and GTP; ATP is used as the phosphate donor. The signal...

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Dettagli Bibliografici
Autori principali: Haseltine, William A., Block, Ricardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1973
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC433543/
https://ncbi.nlm.nih.gov/pubmed/4576025
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