S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance

BACKGROUND: The tumor microenvironment plays a determinative role in stimulating tumor progression and metastasis. Notably, tumor-stroma signals affect the pattern of infiltrated immune cells and the profile of tumor-released cytokines. Among the known molecules that are engaged in stimulating the m...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Grum-Schwensen, Birgitte, Klingelhöfer, Jörg, Beck, Mette, Bonefeld, Charlotte Menné, Hamerlik, Petra, Guldberg, Per, Grigorian, Mariam, Lukanidin, Eugene, Ambartsumian, Noona
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335362/
https://ncbi.nlm.nih.gov/pubmed/25884510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1034-2
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