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High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients

BACKGROUND: The metastasis-associated in colon cancer 1 (MACC1) gene has been identified as prognostic biomarker for colorectal cancer (CRC). Here, we aimed at the refinement of risk assessment by separate and combined survival analyses of MACC1 expression with any of the markers KRAS mutated in cod...

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Publicado en:Mol Cancer
Autores principales: Ilm, Katharina, Kemmner, Wolfgang, Osterland, Marc, Burock, Susen, Koch, Gudrun, Herrmann, Pia, Schlag, Peter M, Stein, Ulrike
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335361/
https://ncbi.nlm.nih.gov/pubmed/25742883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0316-2
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