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High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients

BACKGROUND: The metastasis-associated in colon cancer 1 (MACC1) gene has been identified as prognostic biomarker for colorectal cancer (CRC). Here, we aimed at the refinement of risk assessment by separate and combined survival analyses of MACC1 expression with any of the markers KRAS mutated in cod...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ilm, Katharina, Kemmner, Wolfgang, Osterland, Marc, Burock, Susen, Koch, Gudrun, Herrmann, Pia, Schlag, Peter M, Stein, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335361/
https://ncbi.nlm.nih.gov/pubmed/25742883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0316-2
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