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A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages

The transcription factor (TF) interferon regulatory factor 8 (IRF8) controls both developmental and inflammatory stimulus-inducible genes in macrophages, but the mechanisms underlying these two different functions are largely unknown. One possibility is that these different roles are linked to the a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Mancino, Alessandra, Termanini, Alberto, Barozzi, Iros, Ghisletti, Serena, Ostuni, Renato, Prosperini, Elena, Ozato, Keiko, Natoli, Gioacchino
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335295/
https://ncbi.nlm.nih.gov/pubmed/25637355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257592.114
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