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Leukotriene-C(4) Synthase, a Critical Enzyme in the Activation of Store-independent Orai1/Orai3 Channels, Is Required for Neointimal Hyperplasia
Leukotriene-C(4) synthase (LTC(4)S) generates LTC(4) from arachidonic acid metabolism. LTC(4) is a proinflammatory factor that acts on plasma membrane cysteinyl leukotriene receptors. Recently, however, we showed that LTC(4) was also a cytosolic second messenger that activated store-independent LTC(...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335238/ https://ncbi.nlm.nih.gov/pubmed/25540197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625822 |
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