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Activated microglia mediate axo-glial disruption that contributes to axonal injury in multiple sclerosis

The complex symptoms of chronic multiple sclerosis (MS) are due, in part, to widespread axonal pathology affecting lesioned and non-lesioned areas of the CNS. Here we describe an association between microglial activation and axon/ oligodendrocyte pathology at nodal and paranodal domains in normal ap...

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Détails bibliographiques
Publié dans:J Neuropathol Exp Neurol
Auteurs principaux: Howell, Owain. W., Rundle, Jon. L., Garg, Anurag, Komada, Masayuki, Brophy, Peter. J., Reynolds, Richard
Format: Artigo
Langue:Inglês
Publié: 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335193/
https://ncbi.nlm.nih.gov/pubmed/20838243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181f3a5b1
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