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The novel endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
The Lamina-associated polypeptide, Emerin, MAN1 - (LEM) domain defines a group of nuclear proteins, which bind chromatin through interaction of the LEM motif with the conserved DNA cross-linking protein, Barrier-to-Auto-Integration factor (BAF). Here, we describe a novel LEM protein, annotated in da...
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| Veröffentlicht in: | J Cell Sci |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335191/ https://ncbi.nlm.nih.gov/pubmed/22399800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.098392 |
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