The novel endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo

The Lamina-associated polypeptide, Emerin, MAN1 - (LEM) domain defines a group of nuclear proteins, which bind chromatin through interaction of the LEM motif with the conserved DNA cross-linking protein, Barrier-to-Auto-Integration factor (BAF). Here, we describe a novel LEM protein, annotated in da...

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Publicado no:J Cell Sci
Main Authors: Brachner, Andreas, Braun, Juliane, Ghodgaonkar, Medini, Castor, Dennis, Zlopaša, Livija, Ehrlich, Veronika, Jiricny, Josef, Gotzmann, Josef, Knasmüller, Siegfried, Foisner, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335191/
https://ncbi.nlm.nih.gov/pubmed/22399800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.098392
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