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Conformational Analysis of Thyrotropin Releasing Factor

Conformational energy calculations on thyrotropin releasing factor and on several of its analogues indicate that the central histidyl residue of the native molecule is in an extended conformation. Some derivatives (with a reduced biological activity) have an altered conformation. Since some substitu...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Burgess, Antony W., Momany, Frank A., Scheraga, Harold A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1973
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433518/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4197091/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.5.1456
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