Intracellular fibril formation, calcification, and enrichment of chaperones, cytoskeletal, and intermediate filament proteins in the adult hippocampus CA1 following neonatal exposure to the nonprotein amino acid BMAA

The environmental neurotoxin β-N-methylamino-l-alanine (BMAA) has been implicated in the etiology of neurodegenerative disease, and recent studies indicate that BMAA can be misincorporated into proteins. BMAA is a developmental neurotoxicant that can induce long-term learning and memory deficits, as...

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Vydáno v:Arch Toxicol
Hlavní autoři: Karlsson, Oskar, Berg, Anna-Lena, Hanrieder, Jörg, Arnerup, Gunnel, Lindström, Anna-Karin, Brittebo, Eva B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2014
Témata:
Organ Toxicity and Mechanisms
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335130/
https://ncbi.nlm.nih.gov/pubmed/24798087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1262-2
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