Transcriptional Attenuation Controls Macrolide Inducible Efflux and Resistance in Streptococcus pneumoniae and in Other Gram-Positive Bacteria Containing mef/mel(msr(D)) Elements

Macrolide resistance, emerging in Streptococcus pneumoniae and other Gram-positive bacteria, is increasingly due to efflux pumps encoded by mef/mel(msr) operons found on discrete mobile genetic elements. The regulation of mef/mel(msr) in these elements is not well understood. We identified the mef(E...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chancey, Scott T., Bai, Xianhe, Kumar, Nikhil, Drabek, Elliott F., Daugherty, Sean C., Colon, Thomas, Ott, Sandra, Sengamalay, Naomi, Sadzewicz, Lisa, Tallon, Luke J., Fraser, Claire M., Tettelin, Hervé, Stephens, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335068/
https://ncbi.nlm.nih.gov/pubmed/25695510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116254
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