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Exclusion of the Unfolded Protein Response in Light-Induced Retinal Degeneration in the Canine T4R RHO Model of Autosomal Dominant Retinitis Pigmentosa
PURPOSE: To examine the occurrence of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) following acute light damage in the naturally-occurring canine model of RHO-adRP (T4R RHO dog). METHODS: The left eyes of T4R RHO dogs were briefly light-exposed and retinas collected 3, 6...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335018/ https://ncbi.nlm.nih.gov/pubmed/25695253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115723 |
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