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Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1

Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Lyu, Ying, Su, Xueying, Deng, Jingna, Liu, Shangxin, Zou, Liangqiang, Zhao, Xiaojing, Wei, Suning, Geng, Bin, Xu, Guoheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335001/
https://ncbi.nlm.nih.gov/pubmed/25695774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117536
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