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Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1

Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Lyu, Ying, Su, Xueying, Deng, Jingna, Liu, Shangxin, Zou, Liangqiang, Zhao, Xiaojing, Wei, Suning, Geng, Bin, Xu, Guoheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335001/
https://ncbi.nlm.nih.gov/pubmed/25695774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117536
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