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Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1

Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice...

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Vydáno v:PLoS One
Hlavní autoři: Lyu, Ying, Su, Xueying, Deng, Jingna, Liu, Shangxin, Zou, Liangqiang, Zhao, Xiaojing, Wei, Suning, Geng, Bin, Xu, Guoheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335001/
https://ncbi.nlm.nih.gov/pubmed/25695774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117536
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