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A Polypeptide Region of Bovine Prothrombin Specific for Binding to Phospholipids

The blood-clotting protein prothrombin can be converted to thrombin in free solution by the proteolytic enzyme, activated factor X. When prothrombin is bound to the surface of phospholipid vesicles, the rate of thrombin generation is increased more than 30-fold over the rate of unbound prothrombin....

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gitel, Sanford N., Owen, Whyte G., Esmon, Charles T., Jackson, Craig M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1973
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4514304/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.5.1344
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