Wird geladen...

Evolutionary Signatures amongst Disease Genes Permit Novel Methods for Gene Prioritization and Construction of Informative Gene-Based Networks

Genes involved in the same function tend to have similar evolutionary histories, in that their rates of evolution covary over time. This coevolutionary signature, termed Evolutionary Rate Covariation (ERC), is calculated using only gene sequences from a set of closely related species and has demonst...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Priedigkeit, Nolan, Wolfe, Nicholas, Clark, Nathan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334549/
https://ncbi.nlm.nih.gov/pubmed/25679399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004967
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!