Mechanism of Action of 1-β-D-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole), A New Broad-Spectrum Antiviral Agent

The antiviral activity of the synthetic nucleoside, Virazole (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide), against measles virus in Vero cell cultures was substantially reversed by xanthosine, guanosine, and to a slightly lesser extent by inosine. Virazole 5′-phosphate was subsequently found t...

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Bibliografiska uppgifter
Huvudupphovsmän: Streeter, David G., Witkowski, J. T., Khare, Gyaneshwar P., Sidwell, Robert W., Bauer, Randy J., Robins, Roland K., Simon, Lionel N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1973
Ämnen:
Biological Sciences: Biochemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC433451/
https://ncbi.nlm.nih.gov/pubmed/4197928
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