Proposed Tertiary Structure for the Hypothalamic Thyrotropin-Releasing Factor
Semiempirical energy calculations were performed to determine the conformation of the thyrotropin-releasing factor, L-pyroglutamyl-L-histidyl-L-prolineamide. Our results strongly suggest a “hairpin turn” conformation stabilized by two specific hydrogen bonds. Experimental support for this structure...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1973
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433449/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4577793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.4.1166 |
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