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Retroviral Integrase Structure and DNA Recombination Mechanism

Due to the importance of human immunodeficiency virus type 1 (HIV-1) integrase as a drug target, the biochemistry and structural aspects of retroviral DNA integration have been the focus of intensive research during the past three decades. The retroviral integrase enzyme acts on the linear double-st...

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Publicat a:Microbiol Spectr
Autors principals: Engelman, Alan, Cherepanov, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334468/
https://ncbi.nlm.nih.gov/pubmed/25705574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.MDNA3-0024-2014.
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