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Cost effective assay choice for rare disease study designs

High throughput assays tend to be expensive per subject. Often studies are limited not so much by the number of subjects available as by assay costs, making assay choice a critical issue. We have developed a framework for assay choice that maximises the number of true disease causing mechanisms ‘see...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Campbell, Desmond D, Porsch, Robert M, Cherny, Stacey S, Capra, Valeria, Merello, Elisa, De Marco, Patrizia, Sham, Pak C, Garcia-Barceló, Maria-Mercè
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334400/
https://ncbi.nlm.nih.gov/pubmed/25648394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-015-0226-9
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