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Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells *

Estrogen (E(2)) supports breast cancer cell growth but suppresses invasiveness and both actions are antagonized by anti-estrogens. As a consequence, anti-estrogen treatment may increase the invasive potential of estrogen receptor (ER)+ tumor cell sub-populations that are endocrine resistant due to H...

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Publicado en:Biochem Biophys Res Commun
Main Authors: Patki, Mugdha, Salazar, Marcela d’alincourt, Trumbly, Robert, Ratnam, Manohar
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334377/
https://ncbi.nlm.nih.gov/pubmed/25582774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.01.004
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